[Doc]

Pretty much agree with muse here. A bigger raise pre-flop is more decisive and gives more information about your callers.

I wouldn't fold that flop for that bet against the overwhelming majority of players - I'd really want to be sure he was a complete rock (i.e. he'd just made trip Jacks or Tens) to do that. Again that is an advantage of a bigger pre-flop raise - a rock would probably fold TT or even JJ to a bigger raise.
Against loose aggressive players I could well be against AJ, KQ (Especially), AQ - anything of that nature. Even against 2 pair, you're not actually in terrible trouble - you have a back door straight, two queens for trips and the option of a running pair or pairing the third flop card. I'd be scared of trips, but I'd definitely call here as I said.

The isolation raise is pointless here - it is a very large amount to call against two players showing strength. This is a classic case of a bet (raise in this case) only being called if you are beaten/behind.
I wouldn't be worried about the flush draw - you're up against aggressive players - i.e. they'll probably raise with AKs, or AQs. KQs is about the only credible hand for an aggressive player to check call.

Now, given you had raised the all-in, and got re-raised - call. Even if you saw the hands they had - you're still 13% to win the hand from that flop. It is costing you $16 to win $91 - i.e. you're getting nearly 6 to 1. You'd have to be more than 87% sure that they held these hands or better to fold. You can NEVER be that sure with this type of flop against anyone - let alone an aggressive player.