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Bournemouth v Gillingham
Bournemouth will be without Stephen Cooke (knee), while James Keene has returned to Portsmouth after the conclusion of his three-month loan.
Neil Young and James O'Connor are slight doubts, but boss Sean O'Driscoll hopes both will be fit to play.
Gillingham are without suspended duo Leon Johnson and Andrew Crofts.
Defender Chris Hope is out with a calf injury, while strikers Darren Byfield and Paul Shields and midfielder Alan Pouton are all doubtful.
Bradford v Rotherham
Bradford goalkeeper Donovan Ricketts serves the final instalment of his two-game at Valley Parade.
Lewis Emanuel may continue at centre-back, while Lee Crooks is pushing for a recall.
Managerless Rotherham will be without veteran defender Scott Minto, who is nursing a foot injury.
And Rotherham's on-loan midfielder Paul Evans has returned to Nottingham Forest after being told that he must undergo knee surgery.
Chesterfield v Oldham
Chesterfield could be without five first-team regulars as Mark Allott and Derek Niven join captain Shane Nicholson on the suspended list.
Alex Bailey (hamstring) also misses out, while fellow defender Gareth Davies is doubtful with a hip problem.
Oldham have both Gareth Owen and Guy Branston ruled out through suspension.
Midfielder Richard Butcher is also very doubtful after losing three teeth and suffering a broken nose in the FA Cup defeat at Brentford on Tuesday.
Colchester v MK Dons
Colchester manager Phil Parkinson has no new injury worries as his team looks to extend their 10-game unbeaten run.
Marino Keith and Stephen Hunt remain on the long-term injured list.
MK Dons striker Izale McLeod, who has been strongly linked with Wolves, faces a late fitness test after picking up a muscle strain in training.
McLeod's strike partner Clive Platt is also struggling with an ankle injury, but midfielder Wade Small has recovered from his ankle injury.
Doncaster v Swansea
Doncaster are without Phil McGuire, Tim Ryan, Andy Warrington, Jermaine McSporran and Barry Richardson.
Rovers could also be without New Zealand international David Mulligan again after he missed last week's 3-2 victory at MK Dons with a slight knock.
Swansea will be without striker Adebayo Akinfenwa, who has flown to Nigeria for his grandmother's funeral.
Kristian O'Leary is out with knee ligament damage, but defender Sam Ricketts should be available.
Huddersfield v Southend
David Mirfin and Chris Brandon are both expected to return for Huddersfield after being suspended at Bristol City.
Danny Adams has recovered from a dead leg but will miss the game through suspension and Adnan Ahmed could make his first start of the season.
Southend striker Shaun Goater is out for two weeks with a dislocated collarbone, while Kevin Maher and Bart Griemink are suspended.
Luke Guttridge has returned to fitness and could figure at some stage.
Port Vale v Bristol City
Port Vale may be without nine players with Tony Dinning banned, Clayton Fortune stopped from playing and Gary Mulligan and Mark Innes doubtful.
Robin Hulbert, Michael Walsh, Michael Cummins, Hector Sam and George Abbey are all sidelined through injury.
Bristol City striker Marcus Stewart is suspended for the trip to Vale Park, so on-loan Bas Savage could start.
Luke Wilkshire (hamstring) is fit again, but Dave Partridge's absence continues with a thigh problem.
Swindon v Blackpool
Charlie Comyn-Platt misses out with a thigh injury, while striker Tony Thorpe left the club earlier this week.
Andy Gurney remains a long-term absentee with an Achilles problem, while Christian Roberts (toe) is making progress but will not feature.
Blackpool will be without Ciaran Donnelly and Danny Coid for the trip.
Coid faces at least three months on the sidelines after breaking his ankle, but caretaker-boss Simon Grayson has no other injury concerns.
Tranmere v Brentford
Tranmere manager Brian Little is hoping defenders Ian Goodison (back and calf), Mike Jackson (calf) and Ian Sharps (knee) will be available.
Striker Chris Greenacre has a good chance of starting, but John Achterberg and Chris Dagnall are sidelined.
Brentford's Darren Pratley is ruled out while fellow midfielder Eddie Hutchinson is due a late fitness test.
Defender Andrew Frampton (knee) is still out while Ricky Newman plays his final game before suspension.
Walsall v Hartlepool
Walsall goalkeeper Andy Oakes is in contention after proving his fitness with a good showing in the reserves.
Midfielder Eric Skora, on loan from Preston, is a major doubt with a knee injury, while Darren Wrack is still out with a broken shin.
Hartlepool midfield duo Thomas Butler and Mark Tinkler after recovering from injuries but Michael Proctor is out.
Proctor is suspended Dean McDonald will play his final game for the club before returning to Ipswich.
Yeovil v Barnsley
Yeovil have goalkeeper Chris Weale, skipper and central defender Terry Skiverton andmidfielder Paul Terry all available for selection.
Yeovil are also boosted by the inclusion of Chris Cohen,whose loan spell from West Ham has been extended.
Barnsley may have Nick Colgan back in goal, but Stephen McPhail will not be risked after his knee injury.
Striker Daniel Nardiello is still a few weeks away from full fitness following his long-term hamstring problem